Objective:
To evaluate the efficacy and safety of low-power ultrasound biomodulation (TULIP) for intraocular pressure (IOP) reduction in glaucoma patients.
Approach:
- Mean IOP reduction of approximately 25.8% compared to control.
- No evidence of thermal injury or structural tissue disruption was observed.
- Stability of retinal nerve fiber layer thickness and no progression of visual field indices were noted.
- Bilateral IOP reduction observed in the untreated contralateral eye.
- Small sample size (n=15) and limited follow-up duration.
- Need for larger studies to confirm findings and assess long-term safety and durability.
Key Findings:
Interpretation:
The findings suggest that TULIP may provide a safe and effective noninvasive option for IOP reduction in glaucoma patients, with potential neuro-autonomic mechanisms influencing outcomes.
Limitations:
Conclusion:
TULIP represents a promising approach to IOP management in glaucoma, emphasizing noninvasive treatment and potential for repeated interventions without tissue damage.
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